First – thank you for sharing your story and for the incredible work you do! Without knowing the extent to which your patient’s mobility is limited, I’m not sure whether he would be physically able to play a game like Rush Hour (non-verbal) which requires a bit of dexterity to move vehicles on a grid (www.thinkfun.com/rushhour). I’m wondering if perhaps a puzzle like Izzi (www.thinkfun.com/izzi) which is far less finicky with small pieces would be a better option to try – this edge-matching challenge encourages players to exercise spatial skills and create an array by lining up tiles with matching colored edges. Please send me an email at cfixler@thinkfun.com if this looks like a puzzle you’re interested in trying, and I’ll be glad to send you a copy!